Endocrine Abstracts

Introduction: Decreased bone mass is associated with inflammatory bowel disease (IBD), due to multiple factors, including endocrine disturbances, deficits in calcium and vitamin D, malnutrition, drugs (corticosteroids), chronic inflammation. If in older man and postmenopausal women, the treatment is well established, for young patients is not a general consensus.Case report: We report the case of a 20-year-old, male, nonsmoker, diagnosed with Crohn disea...

Introduction: Vitamin D is a potential immune modulator and low levels are common in inflammatory bowel disease (IBD) patients. The aim of the study was to determine the association between deficient vitamin D and inflammatory profile.Methods: Intestinal (fecal calprotectin) and blood inflammatory profile [erythrocytes sedimentation rate (ESR), protein C reactive, fibrinogen], were performed to all patients. In addition, level of 25 hydroxy vitamin D was...

Introduction: Although patients with inflammatory bowel disease (IBD) -Crohn’s disease (CD) and ulcerative colitis (UC)- are considered prone to malnutrition, studies have shown an increased risk for obesity, especially visceral obesity and metabolic syndrome (MetS). Possible mechanisms involved include dysbiosis, gut microbiome and chronic inflammation. The aim of the study was to assess the prevalence of MetS and obesity in a group of IBD patients.<p class="abstext"...

Introduction: Patients with inflammatory bowel disease (IBD) are at increased risk for decreased bone mass density (BMD), fractures. Preserved muscle mass is important for healthy bones. Low mean mass can be found in these patients due to immobilization, lack of physical activity and glucocorticoids. Our aim was to evaluate the presence of low BMD and muscle mass impact on it.Methods: 64 patients with inflammatory bowel disease (40 with Crohn disease, 24...

Introduction: Chronic hypergastrinemia is no longer an uncommon phenomenon. Zollinger-Ellison syndrome [ZES], chronic atrophic gastritis [CAG] type A, proton pump inhibitors [PPI] therapy, or Helicobacter pylori-induced CAG type B are causes of hypergastrinemia. Serum gastrin levels >1000 pg/ml (> 0 times the upper limit of normal) and PH gastric below 2 is the diagnostic of ZES, but two -thirds of ZES patients have serum gastrin levels below 1000 pg/ml. We present the...